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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Replication Origin

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Biological context of Replication Origin


Anatomical context of Replication Origin


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Gene context of Replication Origin


Analytical, diagnostic and therapeutic context of Replication Origin


  1. Insertion of an R1 plasmid into the origin of replication of the E. coli chromosome: random timing of replication of the hybrid chromosome. Koppes, L., Nordström, K. Cell (1986) [Pubmed]
  2. Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replication. Stillman, B.W., Tamanoi, F., Mathews, M.B. Cell (1982) [Pubmed]
  3. Expression of polyoma early functions in mouse embryonal carcinoma cells depends on sequence rearrangements in the beginning of the late region. Katinka, M., Yaniv, M., Vasseur, M., Blangy, D. Cell (1980) [Pubmed]
  4. Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. Appel, J.D., Fasy, T.M., Kohtz, D.S., Kohtz, J.D., Johnson, E.M. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  5. Mechanism of phage Mu-1 integration: nalidixic acid treatment causes clustering of Mu-1-induced mutations near replication origin. Paolozzi, L., Jucker, R., Calef, E. Proc. Natl. Acad. Sci. U.S.A. (1978) [Pubmed]
  6. A new role for Ran in ensuring precise duplication of chromosomal DNA. Blow, J.J. Cell (2003) [Pubmed]
  7. Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication. Wuarin, J., Buck, V., Nurse, P., Millar, J.B. Cell (2002) [Pubmed]
  8. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Tanaka, T., Knapp, D., Nasmyth, K. Cell (1997) [Pubmed]
  9. E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration. Slater, S., Wold, S., Lu, M., Boye, E., Skarstad, K., Kleckner, N. Cell (1995) [Pubmed]
  10. Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences. Brunier, D., Peeters, B.P., Bron, S., Ehrlich, S.D. EMBO J. (1989) [Pubmed]
  11. Cloning and mapping of the replication origin of Escherichia coli. Yasuda, S., Hirota, Y. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  12. Binding properties of replication protein A from human and yeast cells. Kim, C., Snyder, R.O., Wold, M.S. Mol. Cell. Biol. (1992) [Pubmed]
  13. Replicon rescue: a novel strategy to clone the genomic DNA flanking insertions of integrating shuttle vector DNA. McMahon, T.L., Wilczynska, Z., Barth, C., Fraser, D.J., Pontes, L., Fisher, P.R. Nucleic Acids Res. (1996) [Pubmed]
  14. Nucleotide sequence of the primer RNA for DNA replication of filamentous bacteriophages. Higashitani, N., Higashitani, A., Horiuchi, K. J. Virol. (1993) [Pubmed]
  15. Partition mechanism of F plasmid: two plasmid gene-encoded products and a cis-acting region are involved in partition. Ogura, T., Hiraga, S. Cell (1983) [Pubmed]
  16. Two steps in the assembly of complexes at yeast replication origins in vivo. Diffley, J.F., Cocker, J.H., Dowell, S.J., Rowley, A. Cell (1994) [Pubmed]
  17. Genomic rearrangements in a mouse cell line containing integrated SV40 DNA. Sager, R., Anisowicz, A., Howell, N. Cell (1981) [Pubmed]
  18. The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites. Fuller, R.S., Funnell, B.E., Kornberg, A. Cell (1984) [Pubmed]
  19. Site-specific DNA repair at the nucleosome level in a yeast minichromosome. Smerdon, M.J., Thoma, F. Cell (1990) [Pubmed]
  20. A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Pelham, H.R. Cell (1982) [Pubmed]
  21. Analysis of origin of DNA replication of human papovavirus BK. Deyerle, K.L., Sajjadi, F.G., Subramani, S. J. Virol. (1989) [Pubmed]
  22. Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences. Cohen, S.M., Hatada, S., Brylawski, B.P., Smithies, O., Kaufman, D.G., Cordeiro-Stone, M. Genomics (2004) [Pubmed]
  23. DNA polymerases alpha, delta, and epsilon localize and function together at replication forks in Saccharomyces cerevisiae. Hiraga, S., Hagihara-Hayashi, A., Ohya, T., Sugino, A. Genes Cells (2005) [Pubmed]
  24. Fish oil slows S phase progression and may cause upstream shift of DHFR replication origin ori-beta in CHO cells. Istfan, N.W., Chen, Z.Y., Rex, S. Am. J. Physiol., Cell Physiol. (2002) [Pubmed]
  25. Coordination of replication and transcription along a Drosophila chromosome. MacAlpine, D.M., Rodríguez, H.K., Bell, S.P. Genes Dev. (2004) [Pubmed]
  26. Replication initiates at a confined region during DNA amplification in Sciara DNA puff II/9A. Liang, C., Spitzer, J.D., Smith, H.S., Gerbi, S.A. Genes Dev. (1993) [Pubmed]
  27. The spatial position and replication timing of chromosomal domains are both established in early G1 phase. Dimitrova, D.S., Gilbert, D.M. Mol. Cell (1999) [Pubmed]
  28. A protein that binds to the P1 origin core and the oriC 13mer region in a methylation-specific fashion is the product of the host seqA gene. Brendler, T., Abeles, A., Austin, S. EMBO J. (1995) [Pubmed]
  29. Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates. You, Z., Ishimi, Y., Mizuno, T., Sugasawa, K., Hanaoka, F., Masai, H. EMBO J. (2003) [Pubmed]
  30. The transactivator proteins VP16 and GAL4 bind replication factor A. He, Z., Brinton, B.T., Greenblatt, J., Hassell, J.A., Ingles, C.J. Cell (1993) [Pubmed]
  31. Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo. Dowell, S.J., Romanowski, P., Diffley, J.F. Science (1994) [Pubmed]
  32. GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Takayama, Y., Kamimura, Y., Okawa, M., Muramatsu, S., Sugino, A., Araki, H. Genes Dev. (2003) [Pubmed]
  33. Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells. Takeda, D.Y., Shibata, Y., Parvin, J.D., Dutta, A. Genes Dev. (2005) [Pubmed]
  34. Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Yan, H., Merchant, A.M., Tye, B.K. Genes Dev. (1993) [Pubmed]
  35. Role of the mukB gene in chromosome and plasmid partition in Escherichia coli. Weitao, T., Dasgupta, S., Nordström, K. Mol. Microbiol. (2000) [Pubmed]
  36. The DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides. Lorimer, H.E., Wang, E.H., Prives, C. J. Virol. (1991) [Pubmed]
  37. Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen. Klausing, K., Scheidtmann, K.H., Baumann, E.A., Knippers, R. J. Virol. (1988) [Pubmed]
  38. Rule governing the division pattern in Escherichia coli minB and wild-type filaments. Jaffé, A., Boye, E., D'Ari, R. J. Bacteriol. (1990) [Pubmed]
  39. Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Araki, Y., Kawasaki, Y., Sasanuma, H., Tye, B.K., Sugino, A. Genes Cells (2003) [Pubmed]
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