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Gene Review:

traT - plays a role in APEC complement...

Escherichia coli

Perumal, N.B. et al., Oteo, J. et al., Lavigne, J.P. et al.

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Disease relevance of traT

Ten VFs were less prevalent (p <0.05) in the ESBL isolates than the susceptible E. coli, while iutA and traT were more prevalent in ESBL isolates (p <0.05) [1].

High impact information on traT

The product of the Escherichia coli sex factor F traT gene (TraTp), an outer membrane protein of Mr = 25,000, is covalently modified in vivo by the addition of glycerol and fatty acids [2].
The product of the F sex factor traT surface exclusion gene is a lipoprotein [2].
All except one of the 27 isolates tested for genetic virulence markers harbored the same three virulence genes: iutA and fyuA (siderophores), and traT (serum survival factor) [3].

References

Virulence genotype and nematode-killing properties of extra-intestinal Escherichia coli producing CTX-M beta-lactamases. Lavigne, J.P., Blanc-Potard, A.B., Bourg, G., Moreau, J., Chanal, C., Bouziges, N., O'callaghan, D., Sotto, A. Clin. Microbiol. Infect. (2006) [Pubmed]
The product of the F sex factor traT surface exclusion gene is a lipoprotein. Perumal, N.B., Minkley, E.G. J. Biol. Chem. (1984) [Pubmed]
Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions. Oteo, J., Navarro, C., Cercenado, E., Delgado-Iribarren, A., Wilhelmi, I., Orden, B., García, C., Miguelañez, S., Pérez-Vázquez, M., García-Cobos, S., Aracil, B., Bautista, V., Campos, J. J. Clin. Microbiol. (2006) [Pubmed]

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