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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

insig1  -  insulin induced gene 1

Danio rerio

 
 
 
 
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High impact information on insig1

  • The combined actions of insig-1 and -2 permit feedback regulation of cholesterol synthesis over a wide range of sterol concentrations [1].

References

  1. Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Yabe, D., Brown, M.S., Goldstein, J.L. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
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