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Gene Review:

floR - florfenicol-chloramphenicol exporter

Pasteurella multocida

Kehrenberg, C. et al., Kehrenberg, C. et al.

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Disease relevance of floR

OBJECTIVES: A florfenicol-resistant Pasteurella trehalosi isolate from a calf was investigated for the presence and the location of the gene floR [1].

High impact information on floR

CONCLUSIONS: The results of this study showed that in the bovine pathogen P. trehalosi, floR-mediated resistance to chloramphenicol and florfenicol was associated with a plasmid, which also carried functionally active genes for resistance to sulphonamides (sul2) and chloramphenicol (catA3) [1].
CONCLUSIONS: The results of this study showed that a plasmid-borne floR gene was responsible for chloramphenicol and florfenicol resistance in the bovine respiratory tract pathogen P. multocida [2].

References

Plasmid-mediated florfenicol resistance in Pasteurella trehalosi. Kehrenberg, C., Meunier, D., Targant, H., Cloeckaert, A., Schwarz, S., Madec, J.Y. J. Antimicrob. Chemother. (2006) [Pubmed]
Plasmid-borne florfenicol resistance in Pasteurella multocida. Kehrenberg, C., Schwarz, S. J. Antimicrob. Chemother. (2005) [Pubmed]

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