The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia

Table of contents

About

Terms

 

Gene Review: 

ApepP  -  Aminopeptidase P

Drosophila melanogaster

Synonyms: AP-P, Apep[P], CG6291, DAP-P, Daminopep-p, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on ApepP

  • Receptor cells in the olfactory epithelium exhibited strong AP-P like immunoreaction (ir) [1].
  • The distribution of this enzyme was studied immunocytochemically in the forebrain of frog Microhyla ornata using antisera directed against cytosolic aminopeptidase P (DAP-P) of Drosophila melanogaster [1].
  • The enzyme aminopeptidase P (AP-P) is encountered in diverse vertebrate and invertebrate phyla and is known to act on proteins and peptides by releasing their N-terminal amino acid when the penultimate amino acid is proline [1].
  • Immunoblot analysis showed that DAP-P is located exclusively in the cytosol and is temporally regulated during Drosophila development [2].
  • The deduced amino acid sequence was 48% identical and 66% similar to rat and human cytosolic aminopeptidase P. Amino acids important for catalytic activity and the metal binding ligands were found to be conserved between Drosophila AP-P and its mammalian homologues [2].
 

Analytical, diagnostic and therapeutic context of ApepP

References

  1. Distribution of aminopeptidase P like immunoreactivity in the olfactory system and brain of frog, Microhyla ornate. Bhargava, S., Kulkarni, G.V., Deobagkar, D.D., Deobagkar, D.N. Neurosci. Lett. (2006) [Pubmed]
  2. A cytosolic form of aminopeptidase P from Drosophila melanogaster: molecular cloning and characterization. Kulkarni, G.V., Deobagkar, D.D. J. Biochem. (2002) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities