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Gene Review:

STAT6 - signal transducer and activator of...

Bos taurus

Enaida, H. et al., Bartoli, M. et al.

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High impact information on STAT6

Here, we show that VEGF induces tyrosine phosphorylation and nuclear translocation of STAT1 and STAT6 [1].

Regulatory relationships of STAT6

These molecules were tyrosine phosphorylated under culture conditions used, and the phosphorylation of Tyk2 and Stat6 was specifically enhanced by VEGF stimulation [2].

References

Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells. Bartoli, M., Gu, X., Tsai, N.T., Venema, R.C., Brooks, S.E., Marrero, M.B., Caldwell, R.B. J. Biol. Chem. (2000) [Pubmed]
VEGF-dependent signaling in retinal microvascular endothelial cells. Enaida, H., Kabuyama, Y., Oshima, Y., Sakamoto, T., Kato, K., Kochi, H., Homma, Y. Fukushima journal of medical science. (1999) [Pubmed]

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