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Gene Review:

ANKRD37 - ankyrin repeat domain 37

Homo sapiens

Synonyms: Ankyrin repeat domain-containing protein 37, LPR2BP, Low-density lipoprotein receptor-related protein 2-binding protein, Lrp2bp, hLrp2bp

Li, J. et al., Benita, Y.

Yair Benita,

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Disease relevance of ANKRD37

RT-PCR revealed that hLrp2bp was mainly expressed in the human testis, small intestine, colon and blood leukocytes, and in human pancreatic adenocarcinoma cells [1].

High impact information on ANKRD37

The hLrp2bp gene was located in chromosome 4q35 and the conserved ankyrin repeat domains were located between amino acid residues 10 and 116 [1].
ANKRD37 is a direct target of transcription factor HIF-1 and is highly induced in hypoxia [2]

References

Molecular cloning and characterization of a novel human gene containing 4 ankyrin repeat domains. Li, J., Ji, C., Zheng, H., Fei, X., Zheng, M., Dai, J., Gu, S., Xie, Y., Mao, Y. Cell. Mol. Biol. Lett. (2005) [Pubmed]
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. Benita, Y., Kikuchi, H., Smith, A.D., Zhang, M.Q., Chung, D.C., Xavier, R.J. Nucleic. Acids. Res. (2009) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

ANKRD37	Bos taurus
ANKRD37	Canis lupus familiaris
ankrd37	Danio rerio
LOC100426380	Macaca mulatta
Ankrd37	Mus musculus
ANKRD37	Pan troglodytes
Ankrd37	Rattus norvegicus
ankrd37	Xenopus (Silurana) tropicalis

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