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Gene Review:

sced - scrambled

Drosophila melanogaster

Synonyms: CG3273, CT9143, Dmel\CG3273, Sced

Stevenson, V. et al., Stevenson, V.A. et al.

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High impact information on sced

Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization [1].
CONCLUSIONS: The Drosophila Arp2/3 complex and Scrambled protein are required for actin cap expansion and pseudocleavage furrow formation during the syncytial blastoderm divisions [2].

Other interactions of sced

The scrambled gene is also required for cap expansion and furrow assembly, and Scrambled is required for Arp2/3 localization to the cap margins [2].

References

Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization. Stevenson, V.A., Kramer, J., Kuhn, J., Theurkauf, W.E. Nat. Cell Biol. (2001) [Pubmed]
Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos. Stevenson, V., Hudson, A., Cooley, L., Theurkauf, W.E. Curr. Biol. (2002) [Pubmed]

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