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Gene Review

Or43b  -  Odorant receptor 43b

Drosophila melanogaster

Synonyms: 25A.1/43, 43b, AN7, CG17853, DOR25A.1, ...
 
 
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High impact information on Or43b

  • Putative Drosophila odor receptor OR43b localizes to dendrites of olfactory neurons [1].
  • We show the OR43b gene on the balancer chromosome SM5 is expressed at reduced levels and contains nucleotide polymorphisms predicted to alter two amino acids in the receptor, including an arginine(128) to proline substitution in the first extracellular loop [1].
  • Or83b, a receptor expressed in a large fraction of olfactory neurons including Or43b neurons, does not confer odor responsiveness in the absence of Or43b [2].

References

  1. Putative Drosophila odor receptor OR43b localizes to dendrites of olfactory neurons. Elmore, T., Smith, D.P. Insect Biochem. Mol. Biol. (2001) [Pubmed]
  2. Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum. Elmore, T., Ignell, R., Carlson, J.R., Smith, D.P. J. Neurosci. (2003) [Pubmed]
 
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