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Gene Review

Nrk  -  Neurospecific receptor kinase

Drosophila melanogaster

Synonyms: CG4007, DNRK, DmHD-434, Dmel\CG4007, Dnrk, ...
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High impact information on Nrk

  • During Drosophila embryogenesis, the Dnrk gene is expressed specifically in the developing nervous system [1].
  • A twelfth insertion disrupts two genes, Nrk, a "neurospecific" receptor tyrosine kinase, and Tpp, which encodes a neuropeptidase [2].
  • ROR1, ROR2 and MUSK are receptor-type tyrosine kinases with extracellular Fz domain, while MFRP is type II transmembrane protein with extracellular Fz domain [3].
  • ROR1, ROR2, MUSK and MFRP are predicted to transduce or regulate WNT signaling [3].
  • Here, we identified and characterized rat Ror1 and Ror2 genes by using bioinformatics [3].


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