The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

musk  -  muscle, skeletal, receptor tyrosine kinase

Danio rerio

Synonyms: SO:0000704, fj98e12, si:busm1-57f23.3, si:dz46m7.2, si:dz57f23.3, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on musk

  • We demonstrate that unplugged is transiently expressed in cells adjacent to the choice point and that unplugged signaling before the arrival of growth cones induces changes in the extracellular environment [1].
  • Mutations in two genes, nevermind (nev) and macho (mao), affect axonal projection in the optic tectum, whereas axon formation and elongation of motorneurons are disrupted by mutations in the diwanka (diw) and the unplugged (unp) genes [2].
  • We also show that secondary motor neurons, most similar to those in birds and mammals, depend on the unplugged gene to navigate a choice point, suggesting that primary and secondary motor neurons share common mechanisms controlling axonal path selection [3].
  • Finally, we report that unplugged larvae display a striking pharyngeal arch defect, consistent with a dual function of the unplugged gene in axonal guidance and cell motility [3].

References

  1. Zebrafish unplugged reveals a role for muscle-specific kinase homologs in axonal pathway choice. Zhang, J., Lefebvre, J.L., Zhao, S., Granato, M. Nat. Neurosci. (2004) [Pubmed]
  2. Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Granato, M., van Eeden, F.J., Schach, U., Trowe, T., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., Nüsslein-Volhard, C. Development (1996) [Pubmed]
  3. A dual role for the zebrafish unplugged gene in motor axon pathfinding and pharyngeal development. Zhang, J., Malayaman, S., Davis, C., Granato, M. Dev. Biol. (2001) [Pubmed]
 
WikiGenes - Universities