Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Khc-73 - Kinesin heavy chain 73

Drosophila melanogaster

Synonyms: CG8183, DmKIN73, DmKin73, DmKlp73, Dmel\CG8183, ...

Li, H.P. et al., Hanada, T. et al.

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High impact information on Khc-73

The amino acid sequence of the motor domain of kinesin-73 protein is most closely related to the motor domains of Caenorhabditis elegans unc-104 and mouse KIF1A [1].
However, later in Drosophila embryo development, expression of the kinesin-73 gene becomes restricted mostly to the central and peripheral nervous systems [1].
Kinesin-73 mRNA was shown by in situ hybridization to be maternally expressed and widely distributed in the syncytial blastoderm embryo [1].
GAKIN mRNA is ubiquitously expressed, and the predicted amino acid sequence shares significant sequence similarity with the Drosophila kinesin-73 motor protein [2].

References

Kinesin-73 in the nervous system of Drosophila embryos. Li, H.P., Liu, Z.M., Nirenberg, M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes. Hanada, T., Lin, L., Tibaldi, E.V., Reinherz, E.L., Chishti, A.H. J. Biol. Chem. (2000) [Pubmed]

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