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Gene Review

scrib  -  scribbled planar cell polarity protein

Danio rerio

Synonyms: Protein scribble homolog, SO:0000704, Scribble1, llk, scrb1, ...
 
 
 
 
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High impact information on scrib

  • We show that the landlocked locus contains the gene scribble1 (scrb1), and that its zygotic expression is required for migration of the nVII motor neurons mainly in a non cell-autonomous manner [1].
  • The dual roles of the scrb1 gene in both neuronal migration and CE provide a novel insight into the underlying mechanisms of cell movement in vertebrate development [1].

References

  1. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Wada, H., Iwasaki, M., Sato, T., Masai, I., Nishiwaki, Y., Tanaka, H., Sato, A., Nojima, Y., Okamoto, H. Development (2005) [Pubmed]
 
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