Gene Review:
Ark - Apaf-1-related-killer
Drosophila melanogaster
Synonyms:
APAF-1, APAF1, ARK, Apaf-1, Apaf1, ...
- The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila. Chew, S.K., Akdemir, F., Chen, P., Lu, W.J., Mills, K., Daish, T., Kumar, S., Rodriguez, A., Abrams, J.M. Dev. Cell (2004)
- A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration. Geisbrecht, E.R., Montell, D.J. Cell (2004)
- Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Kanuka, H., Sawamoto, K., Inohara, N., Matsuno, K., Okano, H., Miura, M. Mol. Cell (1999)
- The two Drosophila cytochrome C proteins can function in both respiration and caspase activation. Arama, E., Bader, M., Srivastava, M., Bergmann, A., Steller, H. EMBO J. (2006)
- The role of ARK in stress-induced apoptosis in Drosophila cells. Zimmermann, K.C., Ricci, J.E., Droin, N.M., Green, D.R. J. Cell Biol. (2002)
- Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark. Rodriguez, A., Chen, P., Oliver, H., Abrams, J.M. EMBO J. (2002)
- Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Sang, T.K., Li, C., Liu, W., Rodriguez, A., Abrams, J.M., Zipursky, S.L., Jackson, G.R. Hum. Mol. Genet. (2005)
- Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer. Yu, X., Wang, L., Acehan, D., Wang, X., Akey, C.W. J. Mol. Biol. (2006)
- Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC. Igaki, T., Yamamoto-Goto, Y., Tokushige, N., Kanda, H., Miura, M. J. Biol. Chem. (2002)