Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

cdk8 - cyclin-dependent kinase 8

Danio rerio

Synonyms: Cell division protein kinase 8, Cyclin-dependent kinase 8, Mediator complex subunit cdk8, Mediator of RNA polymerase II transcription subunit cdk8, SO:0000704

Brabazon, E.D. et al.

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High impact information on cdk8

Northern blotting and whole mount in situ hybridisation revealed expression of zebrafish cdk8 maternally, following the onset of zygotic transcription at the mid-blastula transition (MBT) and throughout embryonic development [1].
It is highly conserved, sharing 79% DNA and 95% amino acid sequence identity with human cdk8, thereby indicating an important role for the protein [1].

References

Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development. Brabazon, E.D., Bree, R.T., Carton, M.W., Grealy, M., Byrnes, L. Biochim. Biophys. Acta (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP009936	Anopheles gambiae str. PEST
CDK8	Bos taurus
cdk-8	Caenorhabditis elegans
CDK8	Canis lupus familiaris
Cdk8	Drosophila melanogaster
CDK8	Gallus gallus
CDK8	Homo sapiens
CDK8	Macaca mulatta
Cdk8	Mus musculus
CDK8	Pan troglodytes
Cdk8	Rattus norvegicus
cdk8	Xenopus (Silurana) tropicalis

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