Gene Review:
SEMA3E - sema domain, immunoglobulin domain (Ig),...
Gallus gallus
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High impact information on SEMA3E
- In summary, the data suggest a possible role of chick Sema3E/collapsin-5 in restricting growth of retinal ganglion cell axons to the optic fiber layer [1].
- Time-lapse video recording of chick in vitro cultures revealed a growth cone collapsing activity of recombinant Sema3E/collapsin-5 [1].
Anatomical context of SEMA3E
- Using retinal ganglion cells (RGCs) as a model, we identified the yet uncharacterized chick semaphorin Sema3E/collapsin-5 as a repulsive cue for outgrowing axons [1].
References
- Semaphorin 3E/collapsin-5 inhibits growing retinal axons. Steinbach, K., Volkmer, H., Schlosshauer, B. Exp. Cell Res. (2002) [Pubmed]
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