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Gene Review

IGFL1  -  IGF-like family member 1

Homo sapiens

Synonyms: APRG644, Insulin growth factor-like family member 1, UNQ644, UNQ644/PRO1274
 
 
 
 
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High impact information on IGFL1

  • In H. sapiens, the family is composed of four genes and two pseudogenes that are referred as IGFL1 to IGFL4 and IGFL1P1 and IGFL1P2, respectively [1].
  • Human IGFL genes are clustered together on chromosome 19 within a 35-kb interval [1].
  • IGFL: A secreted family with conserved cysteine residues and similarities to the IGF superfamily [1].
  • IGFL mRNAs display specific expression patterns; they are expressed in fetal tissues, breast, and prostate, and in many cancers as well, and this pattern is consistent with that of the IGF family members [1].

References

  1. IGFL: A secreted family with conserved cysteine residues and similarities to the IGF superfamily. Emtage, P., Vatta, P., Arterburn, M., Muller, M.W., Park, E., Boyle, B., Hazell, S., Polizotto, R., Funk, W.D., Tang, Y.T. Genomics (2006) [Pubmed]
 
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