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Gene Review

KCND1  -  potassium channel, voltage gated Shal...

Homo sapiens

Synonyms: Kv4.1, Potassium voltage-gated channel subfamily D member 1, Voltage-gated potassium channel subunit Kv4.1
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High impact information on KCND1

  • KCND1-specific transcripts were detectable in human brain, heart, liver, kidney, thyroid gland, and pancreas, as revealed by Northern blot and RT-PCR experiments [1].
  • The KCND3 gene contains an additional exon of 57 bp, which is not present in the other two KCND genes and gives rise to the C-terminal splice KCND3L variant with an insertion of 19 amino acids [1].
  • The four known members of the KCND/Kv4 channel family encode voltage-gated potassium channels [1].


  1. Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA). Isbrandt, D., Leicher, T., Waldschütz, R., Zhu, X., Luhmann, U., Michel, U., Sauter, K., Pongs, O. Genomics (2000) [Pubmed]
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