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Gene Review:

Nmt - N-myristoyl transferase

Drosophila melanogaster

Synonyms: 153290_at, CG7436, Dmel\CG7436, Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, ...

Ntwasa, M. et al., Ntwasa, M. et al.

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High impact information on Nmt

Sequence and expression of Drosophila myristoyl-CoA: protein N-myristoyl transferase: evidence for proteolytic processing and membrane localisation [1].
We have also isolated the Drosophila N-myristoyl transferase gene and determined its nucleotide sequence [1].
The enzyme N-myristoyl transferase transfers the 14 carbon fatty acid myristate to an N-terminal glycine residue in a small subset of cytoplasmic proteins [1].
Myristic acid is added to proteins by the enzyme N-myristoyltransferase (NMT) and in this paper we detail the effects on embryonic development of a null mutation in the Drosophila NMT gene [2].

References

Sequence and expression of Drosophila myristoyl-CoA: protein N-myristoyl transferase: evidence for proteolytic processing and membrane localisation. Ntwasa, M., Egerton, M., Gay, N.J. J. Cell. Sci. (1997) [Pubmed]
Drosophila embryos lacking N-myristoyltransferase have multiple developmental defects. Ntwasa, M., Aapies, S., Schiffmann, D.A., Gay, N.J. Exp. Cell Res. (2001) [Pubmed]

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AgaP_AGAP001804	Anopheles gambiae str. PEST
NMT1	Arabidopsis thaliana
NMT1	Bos taurus
NMT1	Canis lupus familiaris
nmt1a	Danio rerio
NMT1	Gallus gallus
NMT1	Homo sapiens
NMT1	Macaca mulatta
Nmt1	Mus musculus
Os01g0708100	Oryza sativa Japonica Group
NMT1	Pan troglodytes
Nmt1	Rattus norvegicus
nmt2	Xenopus (Silurana) tropicalis

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