Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

E(z) - Enhancer of zeste

Drosophila melanogaster

Synonyms: CG6502, Dmel\CG6502, E(Z), E(z)1, EZ, ...

Phillips, M.D. et al., Haun, W.J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on E(z)

The Arabidopsis gene MEDEA displays an imprinted pattern of gene expression and has homology to the Drosophila Polycomb group (PcG) protein Enhancer-of-zeste (E(z)) [1].
Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes [2].
Dominant mutations originally identified as enhancers or suppressors of zeste are gain-of-function alleles of polycombeotic [2].
Here we report that polycombeotic (formerly 1(3)1902), originally identified by a lethal mutation that causes a small-disc phenotype, is also a member of this group of essential genes [2].

References

Genomic imprinting, methylation and molecular evolution of maize Enhancer of zeste (Mez) homologs. Haun, W.J., Laoueillé-Duprat, S., O'connell, M.J., Spillane, C., Grossniklaus, U., Phillips, A.R., Kaeppler, S.M., Springer, N.M. Plant J. (2007) [Pubmed]
Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes. Phillips, M.D., Shearn, A. Genetics (1990) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP012516	Anopheles gambiae str. PEST
EZH2	Bos taurus
EZH2	Canis lupus familiaris
ezh2	Danio rerio
EZH2	Gallus gallus
EZH2	Homo sapiens
EZH2	Macaca mulatta
Ezh2	Mus musculus
EZH2	Pan troglodytes
Ezh2	Rattus norvegicus
ezh2	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share