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Gene Review

msx2  -  msh homeobox 2

Xenopus (Silurana) tropicalis

Synonyms: crs2, fpp, hox8, msh, pfm, ...
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High impact information on msx2

  • A surprising finding was the statistically significant difference in phenotypic changes (p < 0.001 when compared to a buffer-injected group) of embryos microinjected with the mRNA of a mutated form of the msx2 gene (without the homeobox region) [1].

Analytical, diagnostic and therapeutic context of msx2

  • It is proposed that the msx2 overexpression system can be used as a consistent and reliable bioassay to map and study the functions of the msx2 gene during development, especially of the craniofacial region [1].


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