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Gene Review

MSX2  -  msh homeobox 2

Canis lupus familiaris

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Disease relevance of MSX2


High impact information on MSX2

  • The MSX2 gene encodes a homeodomain transcription factor important for normal head and face morphogenesis [1].
  • In this paper we describe the cloning of the canine homologue of MSX2, the determination of its structure, sequence and localization of the gene to dog chromosome 4q23 [1].


  1. The canine homeobox gene MSX2: sequence, chromosome assignment and genetic analysis in dogs of different breeds. Haworth, K., Breen, M., Binns, M., Hopkinson, D.A., Edwards, Y.H. Anim. Genet. (2001) [Pubmed]
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