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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CLDN4  -  claudin 4

Gallus gallus

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High impact information on LOC395144

  • Expression of chimeras containing at least one transmembrane domain of occludin also resulted in an enhanced intracellular accumulation of claudin-4, another transmembrane protein of tight junctions, suggesting that the two proteins may cooperate in the regulation of paracellular permeability [1].


  1. Multiple domains of occludin are involved in the regulation of paracellular permeability. Balda, M.S., Flores-Maldonado, C., Cereijido, M., Matter, K. J. Cell. Biochem. (2000) [Pubmed]
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