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Gene Review

Cldn4  -  claudin 4

Rattus norvegicus

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Disease relevance of Cldn4


High impact information on Cldn4


Biological context of Cldn4

  • Claudin-4 expression was significantly increased in the upper third of the villi in jaundiced rats and an upregulation of its lateral distribution was noted [2].

Anatomical context of Cldn4


Associations of Cldn4 with chemical compounds


Other interactions of Cldn4


  1. A novel strategy for the enhancement of drug absorption using a claudin modulator. Kondoh, M., Masuyama, A., Takahashi, A., Asano, N., Mizuguchi, H., Koizumi, N., Fujii, M., Hayakawa, T., Horiguchi, Y., Watanbe, Y. Mol. Pharmacol. (2005) [Pubmed]
  2. Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: effect of bombesin and neurotensin. Assimakopoulos, S.F., Vagianos, C.E., Charonis, A.S., Alexandris, I.H., Spiliopoulou, I., Thomopoulos, K.C., Nikolopoulou, V.N., Scopa, C.D. World J. Gastroenterol. (2006) [Pubmed]
  3. Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Rahner, C., Mitic, L.L., Anderson, J.M. Gastroenterology (2001) [Pubmed]
  4. Heterogeneity of claudin expression by alveolar epithelial cells. Wang, F., Daugherty, B., Keise, L.L., Wei, Z., Foley, J.P., Savani, R.C., Koval, M. Am. J. Respir. Cell Mol. Biol. (2003) [Pubmed]
  5. Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells. Le Moellic, C., Boulkroun, S., González-Nunez, D., Dublineau, I., Cluzeaud, F., Fay, M., Blot-Chabaud, M., Farman, N. Am. J. Physiol., Cell Physiol. (2005) [Pubmed]
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