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Gene Review

FZD5  -  frizzled family receptor 5

Gallus gallus

Synonyms: FZ-8, FZD8, cFz-8
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High impact information on FZ-8

  • Using the extracellular domain of Frizzled 8 to block Wnt signaling and Wnt3a ligand misexpression to activate WNT signaling, we demonstrate that the Wnt pathway acts mitogenically to expand the populations of neuronal progenitor cells specified by BMP [1].


  1. Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity. Chesnutt, C., Burrus, L.W., Brown, A.M., Niswander, L. Dev. Biol. (2004) [Pubmed]
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