Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Fzd5 - frizzled homolog 5 (Drosophila)

Mus musculus

Synonyms: 5330434N09Rik, AI427138, Frizzled-5, Fz-5, Fz5, ...

Ishikawa, T. et al., van Es, J.H. et al.

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High impact information on Fzd5

Moreover, conditional deletion of the Wnt receptor Frizzled-5 abrogates expression of these genes in Paneth cells in the adult intestine [1].
Fzd5 mRNA was expressed in the yolk sac, eye and lung bud at 9.5 days post coitum [2].
To investigate the physiological roles of frizzled proteins, we isolated and characterized a novel mouse frizzled gene Fzd5 [2].
Using homologous recombination in embryonic stem cells, we have generated Fzd5 knockout mice [2].

Other interactions of Fzd5

Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis [2].

References

Wnt signalling induces maturation of Paneth cells in intestinal crypts. van Es, J.H., Jay, P., Gregorieff, A., van Gijn, M.E., Jonkheer, S., Hatzis, P., Thiele, A., van den Born, M., Begthel, H., Brabletz, T., Taketo, M.M., Clevers, H. Nat. Cell Biol. (2005) [Pubmed]
Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Ishikawa, T., Tamai, Y., Zorn, A.M., Yoshida, H., Seldin, M.F., Nishikawa, S., Taketo, M.M. Development (2001) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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