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Gene Review

LOC395756  -  thrombomucin

Gallus gallus

This record was replaced with 395755.
 
 
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High impact information on LOC395756

  • Single cell analysis of yolk sac cells from 3-d-old chick embryos revealed that thrombomucin is expressed on the surface of both lineage-restricted and multipotent progenitors [1].
  • The phenotype of these cells, expressing the cell surface molecules alpha2beta1 integrin, c-kit, thrombomucin/MEP21, HEMCAM and chL12, reflects functional properties required for cell adhesion, migration and growth factor responsiveness [2].
  • Here we studied the ontogeny of cell-surface antigens HEMCAM, alpha2beta1 integrin, thrombomucin, chL12 and c-kit and their co-expression on prethymic T-cell progenitors [3].

References

  1. Thrombomucin, a novel cell surface protein that defines thrombocytes and multipotent hematopoietic progenitors. McNagny, K.M., Pettersson, I., Rossi, F., Flamme, I., Shevchenko, A., Mann, M., Graf, T. J. Cell Biol. (1997) [Pubmed]
  2. Characterization of prethymic progenitors within the chicken embryo. Lampisuo, M., Liippo, J., Vainio, O., McNagny, K.M., Kulmala, J., Lassila, O. Int. Immunol. (1999) [Pubmed]
  3. Antigenic phenotype of early intra-embryonic lymphoid progenitors in the chicken. Lampisuo, M., Katevuo, K., Lassila, O. Scand. J. Immunol. (1998) [Pubmed]
 
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