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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

LOC395991  -  crescent

Gallus gallus

 
 
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High impact information on LOC395991

  • Finally, the relationship between the hypoblast and the definitive endoderm was defined by following labeled rostral primitive-streak cells over a short period of time as they contributed to the definitive endoderm, and combining this with in situ hybridization with a riboprobe for Crescent, a marker of the hypoblast [1].
  • The homeobox gene Hex and the chick Frizbee homologue Crescent are both expressed prominently within anterior definitive endoderm at the time when removal of this tissue results in forebrain defects, and the possible implications of this are discussed [2].

References

  1. Epiblast and primitive-streak origins of the endoderm in the gastrulating chick embryo. Lawson, A., Schoenwolf, G.C. Development (2003) [Pubmed]
  2. Foregut endoderm is required at head process stages for anteriormost neural patterning in chick. Withington, S., Beddington, R., Cooke, J. Development (2001) [Pubmed]
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