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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

KCNJ2  -  potassium inwardly-rectifying channel,...

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Analytical, diagnostic and therapeutic context of KCNJ2

  • Site-directed mutagenesis was used to change Gln-125 to Glu (the residue in IRK1), resulting in a channel with a single-channel conductance of 28 picosiemens and a Ba2+ block of K1/2 = 2 microM [1].

References

  1. Permeation properties and differential expression across the auditory receptor epithelium of an inward rectifier K+ channel cloned from the chick inner ear. Navaratnam, D.S., Escobar, L., Covarrubias, M., Oberholtzer, J.C. J. Biol. Chem. (1995) [Pubmed]
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