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Gene Review:

CD1.1 - CD1 antigen

Sus scrofa

Larsson, L.C. et al., Cipriani, B. et al.

Larsson, Anderson, Widner, Korsgrent,

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Disease relevance of CD1.1

Upregulation of group 1 CD1 antigen presenting molecules in guinea pigs with experimental autoimmune encephalomyelitis: an immunohistochemical study [1].

High impact information on CD1.1

The CD1.1-/- mice are deficient in NK T cells and the antigen-presenting molecule CD1d1 [2].
A cell suspension was prepared from the ventral mesencephalon of 26-27-day-old pig embryos, and 2 microl was implanted in the right striata of mutant CD1d1 null (CD1.1-/-) mice, NK1.1-depleted mice, and controls [2].

References

Upregulation of group 1 CD1 antigen presenting molecules in guinea pigs with experimental autoimmune encephalomyelitis: an immunohistochemical study. Cipriani, B., Chen, L., Hiromatsu, K., Knowles, H., Raine, C.S., Battistini, L., Porcelli, S.A., Brosnan, C.F. Brain Pathol. (2003) [Pubmed]
Enhanced survival of porcine neural xenografts in mice lacking CD1d1, but no effect of NK1.1 depletion. Larsson, L.C., Anderson, P., Widner, H., Korsgrent, O. Cell transplantation. (2001) [Pubmed]

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