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Gene Review: 

bmp2-b  -  bone morphogenetic protein 2

Xenopus laevis

Synonyms: BMP-2, xBMP-2, xbmp2
 
 
 
 
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High impact information on LOC397873

  • Unlike the closely related BMP-4 gene, the BMP-2 gene is strongly transcribed during oogenesis [1].
  • Microinjection of BMP-2 RNA into the two dorsal blastomeres of 4-cell stage embryos leads to ventralization of developing embryos [1].
  • The results demonstrate that BMP-2 overexpression exerts very similar effects as have previously been described for BMP-4, and they suggest that BMP-2 may act already as a maternal factor in ventral mesoderm formation [1].

References

  1. Bone morphogenetic protein 2 in the early development of Xenopus laevis. Clement, J.H., Fettes, P., Knöchel, S., Lef, J., Knöchel, W. Mech. Dev. (1995) [Pubmed]
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