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Gene Review:

c-ets-1b - c-ets-1b proto-oncogene

Xenopus laevis

Meyer, D. et al., Stiegler, P. et al.

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High impact information on c-ets-1b

Characterization of Xenopus laevis cDNA clones of the c-ets-1 proto-oncogene [1].
Specific transcription can also be observed for ets-1 in the hemangioblastic precursors, in endothelial cells of the forming heart and blood vessels [2].
In neurula and tailbud stages, ets-1 and ets-2 transcripts are detected in neural crest cells and their derivatives [2].
Such a role would be critical for tumor cell dissemination, in addition to the one already ascribed to ets-1 in the expression of proteases specific for the extracellular matrix [2].

References

Characterization of Xenopus laevis cDNA clones of the c-ets-1 proto-oncogene. Stiegler, P., Wolff, C.M., Baltzinger, M., Hirtzlin, J., Senan, F., Meyer, D., Ghysdael, J., Stéhelin, D., Befort, N., Remy, P. Nucleic Acids Res. (1990) [Pubmed]
Ets-1 and Ets-2 proto-oncogenes exhibit differential and restricted expression patterns during Xenopus laevis oogenesis and embryogenesis. Meyer, D., Durliat, M., Senan, F., Wolff, M., Andre, M., Hourdry, J., Remy, P. Int. J. Dev. Biol. (1997) [Pubmed]

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