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Gene Review

not-a  -  notochord homeobox

Xenopus laevis

Synonyms: Xnot-2, Xnot2, Znot, flh, not, ...
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High impact information on LOC397961

  • We have studied the regulation of Xnot by signaling molecules involved in mesoderm induction and regionalization [1].
  • We describe the cloning and expression of Xnot, a novel homeo box-containing gene expressed primarily in the gastrula organizing region [1].
  • Gsc acts in deeper vegetal cells, where it regulates Frzb expression to maintain Xnot expression in the neighbouring notochord territory [2].

Anatomical context of LOC397961

  • Role of Goosecoid, Xnot and Wnt antagonists in the maintenance of the notochord genetic programme in Xenopus gastrulae [2].


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