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Gene Review

alpha-Est4  -  alpha-Esterase-4

Drosophila melanogaster

Synonyms: CG1082, DmalphaE4, Dmel\CG1082, FBgn0015572, aE4, ...
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High impact information on alpha-Est4

  • Esterase-4 and esterase-5 are the products of a duplicated gene [1].
  • Several fitness components in strains of Drosophila mulleri carrying the slow or the fast alleles for the major beta esterase (esterase-4) found in this species, as well as in heterozygous flies in which the slow or fast alleles came from one of the parents, were evaluated [2].
  • At the 16th-20th hour of embryonic development the maternal fractions are accompanied by the manifestation of paternal fractions of the slowly migrating esterase-4 [3].


  1. Structural comparison of two esterases from Drosophila mojavensis isolated by immunoaffinity chromatography. Pen, J., Van Beeumen, J., Beintema, J.J. Biochem. J. (1986) [Pubmed]
  2. Evaluation of fitness components in strains of Drosophila mulleri carrying different genotypes for an esterase. Lourenço, M.F., Ceron, C.R., Carareto, C.M. Cytobios (2001) [Pubmed]
  3. Sequence of expression of paternal and maternal esterases in the ontogeny of Drosophila virilis. Matveeva, N.M., Korochkin, L.I. The Soviet journal of developmental biology. (1975) [Pubmed]
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