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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

mRpL47  -  mitochondrial ribosomal protein L47

Drosophila melanogaster

Synonyms: BcDNA:AT29239, CG9378, Dmel\CG9378, MRP-L47, Rlc1
 
 
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High impact information on Rlc1

  • Rlc1p is important for cytokinesis at all growth temperatures and is essential for this process at lower temperatures [1].
  • Interestingly, all deleterious phenotypes associated with the loss of Rlc1p function are suppressed by deletion of the RLC binding site on Myo2p [1].
  • In addition, a third gene termed Rlc1, is found at a very close proximity downstream to Rlb1 [2].
  • The expression of Rlc1 during embryogenesis is similar, but not identical, to the expression pattern detected for Ras1 [2].

References

  1. Type II myosin regulatory light chain relieves auto-inhibition of myosin-heavy-chain function. Naqvi, N.I., Wong, K.C., Tang, X., Balasubramanian, M.K. Nat. Cell Biol. (2000) [Pubmed]
  2. Differential expression during embryogenesis of three genes clustered in the Ras1 region of Drosophila melanogaster. Ezer, S.T., Sahar, D., Salzberg, A., Lev, Z. Dev. Dyn. (1994) [Pubmed]
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