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Gene Review: 

AP-1mu  -  Adaptor Protein complex 1, mu subunit

Drosophila melanogaster

Synonyms: AP-1mu1, AP-47, AP1mu1, AP47, APmu1, ...
 
 
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High impact information on AP-47

  • The two other Drosophila members of the medium-chain family of clathrin-associated protein complexes, AP47 and mu3, have also been identified and mapped to 85D20-D27 and 6E1-E4, respectively [1].
  • A search of the Drosophila melanogaster expressed sequence tag (EST) database identified orthologs of family members mammalian medium (mu) chain families mu1, mu2, and mu3, of the corresponding AP complexes, and delta-COP, the analogous component of the coatomer (COPI) complex [2].

References

  1. Cloning, mapping and tissue-specific expression of Drosophila clathrin-associated protein AP50 gene. Zhang, Y.Q., Broadie, K. Gene (1999) [Pubmed]
  2. Defective expression of the mu3 subunit of the AP-3 adaptor complex in the Drosophila pigmentation mutant carmine. Mullins, C., Hartnell, L.M., Wassarman, D.A., Bonifacino, J.S. Mol. Gen. Genet. (1999) [Pubmed]
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