High impact information on deltaCOP

• Casein kinase II of Saccharomyces cerevisiae is composed of two distinct catalytic subunits, alpha and alpha', and two distinct regulatory subunits, beta and beta' (Padmanabha, R. and Glover, C. V. C. (1987) J. Biol. Chem. 262, 1829-1835; Bidwai, A. P., Reed, J. C., and Glover, C. V. C. (1994) Arch. Biochem. Biophys. 309, 348-355) [1].
• This article describes developmental analysis of gs(1)N26 mutation. gs(1)N26 is a temperature-sensitive maternal-effect mutation affecting the formation of the germ line (Y. Niki and M. Okada, Wilhelm Roux's Arch. Dev. Biol. 190, 1-10, 1981) [2].
• I. Held (1979, Wilhelm Roux's Arch. 187, 105-127) in triploid flies, that bristle spacing is a function of cell size [3].
• The gene initially was named "Bristle on arista" or "Brista" because one aspect of the phenotype is the formation of leg bristles on the antenna (Sato [1984] Drosophila Information Service 60:180-182; Sunkel and Whittle [1987] Wilhelm Roux's. Arch. Dev. Biol. 196:124-132) [4].
• Each abdominal neuromere of a Drosophila embryo contains about 60 glial cells [Klämbt C, Goodman CS (1991): Glia 4:205-213; Ito et al. (1995): Roux's Arch Dev Biol, 204:284-307] [5].

Biological context of deltaCOP

• A search of the Drosophila melanogaster expressed sequence tag (EST) database identified orthologs of family members mammalian medium (mu) chain families mu1, mu2, and mu3, of the corresponding AP complexes, and delta-COP, the analogous component of the coatomer (COPI) complex [6].

References