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Gene Review

CYP2E1  -  cytochrome P450, family 2, subfamily E,...

Canis lupus familiaris

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Disease relevance of CYP2E1

  • Although cDNAs for the human, rodent, and rabbit forms of CYP2E1 have been isolated and studied extensively, there is an absence of information about canine CYP2E1, despite the fact that the dog is routinely used in drug safety studies [1].


  1. Cloning of canine cytochrome P450 2E1 cDNA: identification and characterization of two variant alleles. Lankford, S.M., Bai, S.A., Goldstein, J.A. Drug Metab. Dispos. (2000) [Pubmed]
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