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Gene Review: 

PLXNA1  -  plexin A1

Gallus gallus

 
 
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High impact information on PLXNA1

  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis [1].
  • Additionally, plexin-A1 has been implicated in dendritic cell function in the immune system [1].
  • Furthermore, we show that plexin-A1 associates with the triggering receptor expressed on myeloid cells-2 (Trem-2), linking semaphorin-signalling to the immuno-receptor tyrosine-based activation motif (ITAM)-bearing adaptor protein, DAP12 [1].

References

  1. Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Takegahara, N., Takamatsu, H., Toyofuku, T., Tsujimura, T., Okuno, T., Yukawa, K., Mizui, M., Yamamoto, M., Prasad, D.V., Suzuki, K., Ishii, M., Terai, K., Moriya, M., Nakatsuji, Y., Sakoda, S., Sato, S., Akira, S., Takeda, K., Inui, M., Takai, T., Ikawa, M., Okabe, M., Kumanogoh, A., Kikutani, H. Nat. Cell Biol. (2006) [Pubmed]
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