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Gene Review: 

AttD  -  Attacin-D

Drosophila melanogaster

Synonyms: Att, Attacin D, CG7629, Dmel\CG7629, att, ...
 
 
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High impact information on AttD

  • Through GmmRel knock-down, we could successfully block the induction of attacin and cecropin expression in the immune responsive tissues fat body and proventriculus (cardia) following microbial challenge [1].
  • The midgut and salivary gland trypanosome infection prevalence, as well as the intensity of midgut parasite infections were found to be significantly higher in flies when attacin and relish expression were knocked down [1].
  • AttD is more divergent and located on a different chromosome [2].

References

  1. Innate immune responses regulate trypanosome parasite infection of the tsetse fly Glossina morsitans morsitans. Hu, C., Aksoy, S. Mol. Microbiol. (2006) [Pubmed]
  2. Expression and evolution of the Drosophila attacin/diptericin gene family. Hedengren, M., Borge, K., Hultmark, D. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
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