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Gene Review:

RGS21 - regulator of G-protein signaling 21

Homo sapiens

Synonyms: Regulator of G-protein signaling 21

Li, X. et al., von Buchholtz, L. et al.

von Buchholtz, Elischer, Tareilus, Gouka, Kaiser, Breer, Conzelmann,

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High impact information on RGS21

Reverse transcription polymerase chain reaction and in situ hybridization experiments demonstrated that RGS21 is expressed selectively in taste tissue where it is found in a subpopulation of sensory cells [1].
RGS21 is a novel regulator of G protein signalling selectively expressed in subpopulations of taste bud cells [1].
In this study, a novel human RGS cDNA (RGS21), 1795 bp long and encoding a 152-amino acid polypeptide, was isolated by large-scale sequencing analysis of a human fetal brain cDNA library [2].

Analytical, diagnostic and therapeutic context of RGS21

PCR analysis showed that RGS21 mRNA was expressed ubiquitously in the 16 tissues examined, implying general physiological roles [2].

References

RGS21 is a novel regulator of G protein signalling selectively expressed in subpopulations of taste bud cells. von Buchholtz, L., Elischer, A., Tareilus, E., Gouka, R., Kaiser, C., Breer, H., Conzelmann, S. Eur. J. Neurosci. (2004) [Pubmed]
Isolation and expression pattern of RGS21 gene, a novel RGS member. Li, X., Chen, L., Ji, C., Liu, B., Gu, J., Xu, J., Zou, X., Gu, S., Mao, Y. Acta Biochim. Pol. (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

RGS21	Bos taurus
RGS21	Canis lupus familiaris
rgs1	Danio rerio
RGS21	Gallus gallus
LOC712826	Macaca mulatta
Rgs21	Mus musculus
RGS21	Pan troglodytes
LOC102551739	Rattus norvegicus
rgs21	Xenopus (Silurana) tropicalis

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