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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Reverse Transcription

 
 
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Disease relevance of Reverse Transcription

 

High impact information on Reverse Transcription

 

Chemical compound and disease context of Reverse Transcription

 

Biological context of Reverse Transcription

 

Anatomical context of Reverse Transcription

 

Associations of Reverse Transcription with chemical compounds

  • The IVS1-containing RNA processing products have several unusual properties, which include: anomalous electrophoretic mobilities on polyacrylamide gels; a block to reverse transcription near the 3' end of IVS1; the presence of a nuclease-resistant component within IVS1 [26].
  • Analysis of 5-bromodeoxyuridine-labeled heavy/light CCC DNA shows that the relaxed circular DNA synthesized in the cytoplasm by reverse transcription is the predominant precursor to the amplified pool of nuclear viral CCC DNA [27].
  • In vivo and in vitro studies revealed that reverse transcription of viral RNA into complementary DNA occurred after acute infection of cells of its natural hosts, mouse and hamster, but not of other species and could be inhibited in vitro by azidothymidine (AZT), indicating that this was mediated by endogenous reverse transcriptase activity [28].
  • The transposition defect results from Mn(2+) accumulation that inhibits reverse transcription [29].
  • Inhibition of reverse transcription in vivo by elevated manganese ion concentration [29].
 

Gene context of Reverse Transcription

 

Analytical, diagnostic and therapeutic context of Reverse Transcription

References

  1. Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells. Kinoshita, S., Chen, B.K., Kaneshima, H., Nolan, G.P. Cell (1998) [Pubmed]
  2. Template switching by RNA polymerase II in vivo. Evidence and implications from a retroviral system. Kandel, E.S., Nudler, E. Mol. Cell (2002) [Pubmed]
  3. Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage. Lupetti, R., Pisarra, P., Verrecchia, A., Farina, C., Nicolini, G., Anichini, A., Bordignon, C., Sensi, M., Parmiani, G., Traversari, C. J. Exp. Med. (1998) [Pubmed]
  4. Rapid increase of mucosal CD4 T cells followed by clearance of intestinal cryptosporidiosis in an AIDS patient receiving highly active antiretroviral therapy. Schmidt, W., Wahnschaffe, U., Schäfer, M., Zippel, T., Arvand, M., Meyerhans, A., Riecken, E.O., Ullrich, R. Gastroenterology (2001) [Pubmed]
  5. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lau, J.Y., Davis, G.L., Kniffen, J., Qian, K.P., Urdea, M.S., Chan, C.S., Mizokami, M., Neuwald, P.D., Wilber, J.C. Lancet (1993) [Pubmed]
  6. An X-to-autosome retrogene is required for spermatogenesis in mice. Bradley, J., Baltus, A., Skaletsky, H., Royce-Tolland, M., Dewar, K., Page, D.C. Nat. Genet. (2004) [Pubmed]
  7. DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Morrish, T.A., Gilbert, N., Myers, J.S., Vincent, B.J., Stamato, T.D., Taccioli, G.E., Batzer, M.A., Moran, J.V. Nat. Genet. (2002) [Pubmed]
  8. Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Eskes, R., Yang, J., Lambowitz, A.M., Perlman, P.S. Cell (1997) [Pubmed]
  9. Mutations in the sarcoglycan genes in patients with myopathy. Duggan, D.J., Gorospe, J.R., Fanin, M., Hoffman, E.P., Angelini, C. N. Engl. J. Med. (1997) [Pubmed]
  10. Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. Shearer, W.T., Quinn, T.C., LaRussa, P., Lew, J.F., Mofenson, L., Almy, S., Rich, K., Handelsman, E., Diaz, C., Pagano, M., Smeriglio, V., Kalish, L.A. N. Engl. J. Med. (1997) [Pubmed]
  11. Absence of hepatitis C viral RNA from saliva and semen of patients with chronic hepatitis C. Fried, M.W., Shindo, M., Fong, T.L., Fox, P.C., Hoofnagle, J.H., Di Bisceglie, A.M. Gastroenterology (1992) [Pubmed]
  12. Novel gene expression mechanism in a fission yeast retroelement: Tf1 proteins are derived from a single primary translation product. Levin, H.L., Weaver, D.C., Boeke, J.D. EMBO J. (1993) [Pubmed]
  13. Specific binding of tryptophan transfer RNA to avian myeloblastosis virus RNA-dependent DNA polymerase (reverse transcriptase). Panet, A., Haseltine, W.A., Baltimore, D., Peters, G., Harada, F., Dahlberg, J.E. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  14. Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo. Suspène, R., Guétard, D., Henry, M., Sommer, P., Wain-Hobson, S., Vartanian, J.P. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  15. Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein. Dyck, J.A., Warrell, R.P., Evans, R.M., Miller, W.H. Blood (1995) [Pubmed]
  16. Tnt1, a mobile retroviral-like transposable element of tobacco isolated by plant cell genetics. Grandbastien, M.A., Spielmann, A., Caboche, M. Nature (1989) [Pubmed]
  17. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. O'Brien, W.A., Koyanagi, Y., Namazie, A., Zhao, J.Q., Diagne, A., Idler, K., Zack, J.A., Chen, I.S. Nature (1990) [Pubmed]
  18. SINEs and LINEs: the art of biting the hand that feeds you. Weiner, A.M. Curr. Opin. Cell Biol. (2002) [Pubmed]
  19. Nonsense mutation R1162X of the cystic fibrosis transmembrane conductance regulator gene does not reduce messenger RNA expression in nasal epithelial tissue. Rolfini, R., Cabrini, G. J. Clin. Invest. (1993) [Pubmed]
  20. Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas. Sato, N., Ueki, T., Fukushima, N., Iacobuzio-Donahue, C.A., Yeo, C.J., Cameron, J.L., Hruban, R.H., Goggins, M. Gastroenterology (2002) [Pubmed]
  21. 52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart. Chan, E.K., Di Donato, F., Hamel, J.C., Tseng, C.E., Buyon, J.P. J. Exp. Med. (1995) [Pubmed]
  22. The molecular basis of hereditary complement factor I deficiency. Vyse, T.J., Morley, B.J., Bartok, I., Theodoridis, E.L., Davies, K.A., Webster, A.D., Walport, M.J. J. Clin. Invest. (1996) [Pubmed]
  23. Stimulation of cyclic guanosine monophosphate production by natriuretic peptide in human biliary cells. St Pierre, M.V., Schlenker, T., Dufour, J.F., Jefferson, D.M., Fitz, J.G., Arias, I.M. Gastroenterology (1998) [Pubmed]
  24. Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus. Kalff, J.C., Carlos, T.M., Schraut, W.H., Billiar, T.R., Simmons, R.L., Bauer, A.J. Gastroenterology (1999) [Pubmed]
  25. Protection of trinitrobenzene sulfonic acid-induced colitis by an interleukin 2-IgG2b fusion protein in mice. Stallmach, A., Wittig, B., Giese, T., Pfister, K., Hoffmann, J.C., Bulfone-Paus, S., Kunzendorf, U., Meuer, S.C., Zeitz, M. Gastroenterology (1999) [Pubmed]
  26. Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Ruskin, B., Krainer, A.R., Maniatis, T., Green, M.R. Cell (1984) [Pubmed]
  27. Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Tuttleman, J.S., Pourcel, C., Summers, J. Cell (1986) [Pubmed]
  28. A non-retroviral RNA virus persists in DNA form. Klenerman, P., Hengartner, H., Zinkernagel, R.M. Nature (1997) [Pubmed]
  29. Inhibition of reverse transcription in vivo by elevated manganese ion concentration. Bolton, E.C., Mildvan, A.S., Boeke, J.D. Mol. Cell (2002) [Pubmed]
  30. Immunoregulatory role of interleukin 10 in rheumatoid arthritis. Katsikis, P.D., Chu, C.Q., Brennan, F.M., Maini, R.N., Feldmann, M. J. Exp. Med. (1994) [Pubmed]
  31. Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro. Montaner, L.J., Doyle, A.G., Collin, M., Herbein, G., Illei, P., James, W., Minty, A., Caput, D., Ferrara, P., Gordon, S. J. Exp. Med. (1993) [Pubmed]
  32. Gene expression, localization, and characterization of endothelin A and B receptors in the human adrenal cortex. Rossi, G., Albertin, G., Belloni, A., Zanin, L., Biasolo, M.A., Prayer-Galetti, T., Bader, M., Nussdorfer, G.G., Palù, G., Pessina, A.C. J. Clin. Invest. (1994) [Pubmed]
  33. Chemokine receptor expression by human intestinal epithelial cells. Dwinell, M.B., Eckmann, L., Leopard, J.D., Varki, N.M., Kagnoff, M.F. Gastroenterology (1999) [Pubmed]
  34. Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa. Nakazawa, A., Watanabe, M., Kanai, T., Yajima, T., Yamazaki, M., Ogata, H., Ishii, H., Azuma, M., Hibi, T. Gastroenterology (1999) [Pubmed]
  35. Retrotransposition of a mouse IAP sequence tagged with an indicator gene. Heidmann, O., Heidmann, T. Cell (1991) [Pubmed]
  36. An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction. Bernhagen, J., Bacher, M., Calandra, T., Metz, C.N., Doty, S.B., Donnelly, T., Bucala, R. J. Exp. Med. (1996) [Pubmed]
  37. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. Furitsu, T., Tsujimura, T., Tono, T., Ikeda, H., Kitayama, H., Koshimizu, U., Sugahara, H., Butterfield, J.H., Ashman, L.K., Kanayama, Y. J. Clin. Invest. (1993) [Pubmed]
  38. Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats. Wang, C., Chao, L., Chao, J. J. Clin. Invest. (1995) [Pubmed]
  39. DNA microarrays and beyond: completing the journey from tissue to cell. Mills, J.C., Roth, K.A., Cagan, R.L., Gordon, J.I. Nat. Cell Biol. (2001) [Pubmed]
 
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