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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Sr-CIII  -  Scavenger receptor class C, type III

Drosophila melanogaster

Synonyms: CG31962, Dmel\CG31962, SR-CIII, dSR-CIII
 
 
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High impact information on Sr-CIII

  • Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells [1].
  • The Drosophila Class B Scavenger Receptor NinaD-I Is a Cell Surface Receptor Mediating Carotenoid Transport for Visual Chromophore Synthesis [2].
  • Interestingly, Sr-CIII and Sr-CIV are polymorphic for premature stop codons [3].
  • Some larger SPs may contain one or more regions important for protein-protein interactions, including clip domains, low-density lipoprotein receptor class A repeats, and scavenger receptor cysteine-rich domains [4].

References

  1. Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells. Ulvila, J., Parikka, M., Kleino, A., Sormunen, R., Ezekowitz, R.A., Kocks, C., Rämet, M. J. Biol. Chem. (2006) [Pubmed]
  2. The Drosophila Class B Scavenger Receptor NinaD-I Is a Cell Surface Receptor Mediating Carotenoid Transport for Visual Chromophore Synthesis. Voolstra, O., Kiefer, C., Hoehne, M., Welsch, R., Vogt, K., von Lintig, J. Biochemistry (2006) [Pubmed]
  3. Elevated polymorphism and divergence in the class C scavenger receptors of Drosophila melanogaster and D. simulans. Lazzaro, B.P. Genetics (2005) [Pubmed]
  4. Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Ross, J., Jiang, H., Kanost, M.R., Wang, Y. Gene (2003) [Pubmed]
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