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Gene Review:

gataa - GATAa protein

Ciona intestinalis

D'Ambrosio, P. et al., Bertrand, V. et al.

Bertrand, Hudson, Caillol, Popovici, Lemaire,

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High impact information on GATAa

Ets1/2 mediates general FGF responsiveness, while the restricted activity of GATAa targets the neural program to the ectoderm [1].
A zygotic transcript was detected at the 110-cell stage in the blastomeres precursors of three different tissues (brain vesicle, mesenchyme, and trunk lateral cells) and the signal was conserved in these territories up to the larval stage, indicating an important role for Ci-GATAa during ascidian differentiation [2].

Analytical, diagnostic and therapeutic context of GATAa

Whole-mount in situ hybridization showed that Ci-GATAa was expressed in a highly dynamic manner [2].

References

Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. Bertrand, V., Hudson, C., Caillol, D., Popovici, C., Lemaire, P. Cell (2003) [Pubmed]
Ci-GATAa, a GATA-class gene from the ascidian Ciona intestinalis: isolation and developmental expression. D'Ambrosio, P., Fanelli, A., Pischetola, M., Spagnuolo, A. Dev. Dyn. (2003) [Pubmed]

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