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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Ci-GATAa, a GATA-class gene from the ascidian Ciona intestinalis: isolation and developmental expression.

Members of the GATA family of zinc finger transcription factors have been shown to play important roles in controlling gene expression in a variety of cell types in many metazoan. Here, we describe the identification of Ci-GATAa, a member of this gene family, in the ascidian Ciona intestinalis. Whole-mount in situ hybridization showed that Ci-GATAa was expressed in a highly dynamic manner. The maternal transcript was evenly distributed in the embryo during early stages of development; however, the signal gradually decreased until it disappeared at the 64-cell stage. A zygotic transcript was detected at the 110-cell stage in the blastomeres precursors of three different tissues (brain vesicle, mesenchyme, and trunk lateral cells) and the signal was conserved in these territories up to the larval stage, indicating an important role for Ci-GATAa during ascidian differentiation.[1]

References

  1. Ci-GATAa, a GATA-class gene from the ascidian Ciona intestinalis: isolation and developmental expression. D'Ambrosio, P., Fanelli, A., Pischetola, M., Spagnuolo, A. Dev. Dyn. (2003) [Pubmed]
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