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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CCNT1  -  cyclin T1

Pan troglodytes

 
 
 
 
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Disease relevance of CCNT1

  • A unique amino acid deletion in the chimpanzee Cyclin T1 does not affect Tat trans-activation of HIV [1].
  • This mutation does not significantly change the trans-activation of HIV-1, suggesting that Tat-Cyclin T1 mediated transcription is not a major barrier to HIV replication in the chimpanzee [1].

References

  1. A unique amino acid deletion in the chimpanzee Cyclin T1 does not affect Tat trans-activation of HIV. Rollman, E.N., Lund, L.H., Sjöstrand, D.E., Leitner, T., Wahren, B.E. AIDS (2002) [Pubmed]
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