Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

fs(1)M3 - female sterile (1) M3

Drosophila melanogaster

Synonyms: CG4790, Dmel\CG4790, Fs(1)K646, fs(1)K646, fs(1)ph, ...

Degelmann, A. et al., Cernilogar, F.M. et al.

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High impact information on fs(1)M3

We have analyzed female-sterile mutations at the X-linked loci fs(1)Nas and fs(1)ph which show allele-specific effects on egg shell structure and embryonic pattern formation [1].
Drosophila vitelline membrane cross-linking requires the fs(1)Nasrat, fs(1)polehole and chorion genes activities [2].

Anatomical context of fs(1)M3

Our results suggest that the products of fs(1)Nas and fs(1)ph are required for the stability of the vitelline membrane and are also involved in a morphogenetic pathway necessary for the correct differentiation of the terminal regions of the embryo [1].

References

Genetic analysis of two female-sterile loci affecting eggshell integrity and embryonic pattern formation in Drosophila melanogaster. Degelmann, A., Hardy, P.A., Mahowald, A.P. Genetics (1990) [Pubmed]
Drosophila vitelline membrane cross-linking requires the fs(1)Nasrat, fs(1)polehole and chorion genes activities. Cernilogar, F.M., Fabbri, F., Andrenacci, D., Taddei, C., Gargiulo, G. Dev. Genes Evol. (2001) [Pubmed]

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