High impact information on hbn

• The current evidence indicates that homeobrain, DRx and orthopedia form a homeobox gene cluster in which all the members are expressed in specific embryonic brain subregions [1].
• Homeobrain, a novel paired-like homeobox gene is expressed in the Drosophila brain [1].
• Expression of homeobrain initiates during the blastoderm stage in the anterior dorsal head primordia and the gene is persistently expressed in these cells which form parts of the brain during later embryonic stages [1].
• We report the isolation and expression of a gene with high similarity to Drosophila melanogaster homeobrain from the polychaete annelid Capitella sp. I. The homeobrain-like (hbnl) gene is a paired-like gene that contains a conserved homeodomain, octapeptide region, alanine stretches, and an OAR domain [2].

Other interactions of hbn

• In addition, the localized brain expression patterns of homeobrain and DRx resemble each other [1].

References