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Gene Review

MC1R  -  melanocortin 1 receptor (alpha melanocyte...

Canis lupus familiaris

Synonyms: MC1-R, MSH-R
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High impact information on MC1R

  • The amino acid sequence for the melanocortin receptor 1 gene (MC1R) was examined in 17 dogs with melanistic masks from seven breeds, 19 dogs without melanistic masks, and 7 dogs in which their coat color made the mask difficult to distinguish [1].
  • An SNP is used to map MC1R to dog chromosome 5 [2].


  1. MC1R studies in dogs with melanistic mask or brindle patterns. Schmutz, S.M., Berryere, T.G., Ellinwood, N.M., Kerns, J.A., Barsh, G.S. J. Hered. (2003) [Pubmed]
  2. An SNP is used to map MC1R to dog chromosome 5. Schmutz, S.M., Moker, J.S., Berryere, T.G., Christison, K.M., Dolf, G. Anim. Genet. (2001) [Pubmed]
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