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Gene Review

RAPGEF6  -  Rap guanine nucleotide exchange factor...

Homo sapiens

Synonyms: KIA001LB, PDZ domain-containing guanine nucleotide exchange factor 2, PDZ-GEF2, PDZGEF2, RA-GEF-2, ...
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High impact information on RAPGEF6


Biological context of RAPGEF6


Associations of RAPGEF6 with chemical compounds


Other interactions of RAPGEF6


  1. Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia. Chen, X., Wang, X., Hossain, S., O'neill, F.A., Walsh, D., Pless, L., Chowdari, K.V., Nimgaonkar, V.L., Schwab, S.G., Wildenauer, D.B., Sullivan, P.F., van den Oord, E., Kendler, K.S. Hum. Mol. Genet. (2006) [Pubmed]
  2. Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras. Gao, X., Satoh, T., Liao, Y., Song, C., Hu, C.D., Kariya Ki, K., Kataoka, T. J. Biol. Chem. (2001) [Pubmed]
  3. Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions. Kozlov, G., Banville, D., Gehring, K., Ekiel, I. J. Mol. Biol. (2002) [Pubmed]
  4. ESI-MS and FTIR studies of the interaction between the second PDZ domain of hPTP1E and target peptides. Papp, R., Ekiel, I., English, A.M. Biochem. Cell Biol. (2003) [Pubmed]
  5. Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. Kuiperij, H.B., de Rooij, J., Rehmann, H., van Triest, M., Wittinghofer, A., Bos, J.L., Zwartkruis, F.J. Biochim. Biophys. Acta (2003) [Pubmed]
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